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当前位置:首页产物中心免疫学抗体A02166MonoRab™ Rabbit Anti-Humanized VHH Antibody Biotin

MonoRab™ Rabbit Anti-Humanized VHH Antibody Biotin
产物介绍:

MonoRab™ Rabbit Anti-Humanized VHH Antibody [Biotin], mAb:The product is specific for Humanized VHH antibodies and Camelid (Llama, Alpaca, and Camel) heavy chain antibodies (IgG2&3), but does not reco

产物型号:A02166

更新时间:2025-11-05

厂商性质:代理商

访&苍产蝉辫;问&苍产蝉辫;量&苍产蝉辫;:9

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产物介绍

The product is specific for Humanized VHH antibodies and Camelid (Llama, Alpaca, and Camel) heavy chain antibodies (IgG2&3), but does not recognize the camelid conventional antibody (IgG1).


产物概述
SpecificityThe product is specific for Humanized VHH antibodies and Camelid (Llama, Alpaca, and Camel) heavy chain antibodies (IgG2&3), but does not recognize the camelid conventional antibody (IgG1).
Host SpeciesRabbit
ImmunogenVHH antibody
Species ReactivityIt has no cross-reactivity with mouse, rat, rabbit, or goat immunoglobulins.
ConjugateBiotin
应用指导
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ApplicationRecommended Usage
ELISA1:5,000-1:10,000
Flow Cytometry1:100-1:1,000
产物属性
FormLiquid
Storage BufferSupplied in PBS (pH 7.2), containing 10 mg/ml BSA, 0.02% sodium azide and 50% glycerol.
Concentration0.5 mg/ml
Storage InstructionsStore at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
PurificationProtein A affinity column
IsotypeRabbit IgG
ClonalityMonoclonal
Clone ID45H8
NoteGenScript can customize this product per customer's request including product size, buffer components, etc.

MonoRab™ Rabbit Anti-Humanized VHH Antibody Biotin, mAb

技术背景
Target BackgroundA camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.
SynonymsBiotin conjugated rabbit anti-Humanized VHH, single-domain antibody monoclonal antibody (Min X Ms, Rt, Rb, Gt).
Reference1. Immunogenicity and humanization of single-domain antibodies.
2. Properties, production, and applications of camelid single-domain antibody fragments. 


For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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